If you notice your computer connecting to OSCEX-en.url.trendmicro.com, presumably from installing a firewall, or other security component…  Don’t worry.

That is, assuming your using a security / antivirus suite from Trend Micro.  That server, is part of their new clound initiaitive, and used for virus pattern detection.  So don’t block this server, or your antivirus package will be partially crippled.